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威尼斯手机版所有网站:丁霞

发布日期:2018年10月14日

  丁霞,医学博士,美国Morehouse医学院分子及细胞生物学博士后。教授、研究员、主任医师,博士研究生导师,博士后指导老师。威尼斯手机版所有网站医院管理处处长。高等学校学科创新引智基地—威尼斯手机版所有网站中西医结合学科创新引智基地的负责人。2007年入选教育部“新世纪优秀人才支持计划”。2014年度荣获科技部“中青年科技创新领军人才”称号。2017年获国家“万人计划”科技创新领军人才称号。先后主持了包括国家科技部“十一五”国家科技支撑计划课题、科技部国际科技合作计划项目课题、国家自然科学基金课题等在内的国家及省部级重大课题14项,授权专利7项,获得国际及省部级科技奖项8项,在消化系统疾病的临床及基础研究领域取得了丰硕成果,先后发表SCI论文47篇。主编及参编著作5部。主要的研究方向为消化系统疾病的基础与临床研究及中药抗肿瘤研究。临床擅长治疗急、慢性胃炎,胃癌前病变,反流性食管炎,消化性溃疡,脂肪肝,酒精性肝。愿剐,便秘,功能性消化不良,肠易激综合征,溃疡性结肠炎以及胃癌、肠癌等消化系统疾病。

  近年来发表论文

  [1] Zhang Y, Liu Y, Li Y, Zhao X, Zhuo L, Zhou A, Zhang L, Su Z, Chen C, Du S, Liu D, Ding X*. Validating traditional Chinese syndrome features in varied stages of chronic gastritis malignant transformation: study protocol for a cross-sectional study. BMJ Open. 2018;8(8): e020939. [Corresponding author]

  [2] Zhang Y, Liu Y, Li Y, Zhao X, Zhuo L, Zhou A, Zhang L, Su Z, Chen C, Du S, Liu D, Ding X*. Hierarchical and Complex System Entropy Clustering Analysis Based Validation for Traditional Chinese Medicine Syndrome Patterns of Chronic Atrophic Gastritis. J Altern Complement Med. 2018, 22. [Corresponding author]

  [3] Yuan X, Yao PY, Jiang J, Zhang Y, Su Z, Yao W, Wang X, Gui P, Mullen M, Henry C, Ward T, Wang W, Brako L, Tian R, Zhao X, Wang F, Cao X, Wang D, Liu X, Ding X, Yao X. MST4 kinase phosphorylates ACAP4 protein to orchestrate apical membrane remodeling during gastric acid secretion. The Journal of Biological Chemistry. 2017;292(39):16174-16187.

  [4] Mo F, Zhuang X, Liu X, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, Yao X. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nature Chemical Biology, 2016, 12(4):226.

  [5] Zhang Y, Zhou A, Liu Y, Zhao Y, Zhang L, Sun L, Du S, Yang Q, Song X, Liang C, Ding X*. Exploratory Factor Analysis for Validating Traditional Chinese Syndrome Patterns of Chronic Atrophic Gastritis. Evid Based Complement Alternat Med. 2016:6872890. [Corresponding author]

  [6] Gregory Adams J, Zhou J, Wang W, Wu H, Quan J, Liu Y, Xia P, Wang Z, Zhou S, Jiang J, Mo F, Zhuang X, Thomas K, Hill DL, Aikhionbare FO, He P, Liu X, Ding X, Yao X. The Microtubule Plus End Tracking Protein TIP150 Interacts with Cortactin to Steer Directional Cell Migration. J Biol Chem. 2016, 23;291(39):20692-706.

  [7] Yin Zhang, Li Zhang, Xia Zhao, Yue Liu, Shiyu Du, Jian Li, Ting Liu, Fusheng Liu, Zeqi Su, Yuyong Jiang, Xia Ding*. Symptom characteristics and prevalence of qi deficiency syndrome in people of varied health status and ages: A multicenter cross-sectional study. Journal of Traditional Chinese Medical Sciences. 2015, 2(3): 173-182

  [8] Zhu L, Wang Z, Wang W, Wang C, Hua S, Su Z, Brako L, Garcia-Barrio M, Ye M, Wei X, Zou H, Ding X, Liu L*, Liu X*, Yao X*. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis. J Biol Chem. 2015, 290(45):27053-66.

  [9] Hao Jiang, Wenwen Wang, Yin Zhang, William W. Yao, Jiying Jiang, BoQin, Wendy Y. Yao, Fusheng Liu, Huihui Wu, Tarsha L. Ward, Chun Wei Chen, Lifang Liu, Xia Ding*, Xing Liu*, and Xuebiao Yao*. Cell Polarity Kinase MST4 Cooperates with cAMP-dependent Kinase to Orchestrate Histamine-stimulated Acid Secretion in Gastric Parietal Cells. J Biol Chem. 2015, 290(47):28272-85. [Corresponding author]

  [10] Dan Cao, Zeqi Su, Wenwen Wang, Huihui Wu, Xing Liu, Saima Akram, Bo Qin, Jiajia Zhou, Xiaoxuan Zhuang, Gregory Adams, Changjiang Jin, Xiwei Wang, Lifang Liu, Donald L. Hill, Dongmei Wang*, Xia Ding*, Xuebiao Yao*. Signaling scaffold protein IQGAP1 interacts with microtubule plus-end tracking protein SKAP and links dynamic microtubule plus-end to steer cell migration. J Biol Chem. 2015, 290(39):23766-80. [Corresponding author]

  [11] Yu H, Zhou J, Takahashi H, Yao W, Suzuki Y, Yuan X, Yoshimura SH, Zhang Y, Liu Y, Emmett N, Bond V, Wang D, Ding X, Takeyasu K, Yao X*. Spatial control of proton pump H, K-ATPase docking at the apical membrane by phosphorylation-coupled ezrin-syntaxin 3 interaction. J Biol Chem. 2014, 289(48):33333-42.

  [12] Zhang Y, Liu Y, Li XP, Li J, Li XF, Chen L, Jiang YY, Yu H, Shi N, Han M, Ye H, Lin ZH, Chen YZ, Liu FS, Ding X*. Evidence-based Novel Changes in Prevalence and Symptom Characteristics of Spleen Deficiency Syndrome in Persons of Varied Health Status and Different Ages: A Cross-sectional Observational Study. Evidence-Based Complementary and Alternative Medicine. Evid Based Complement Alternat Med. 2014:818235. [Corresponding author]

  [13] Yin Zhang, Yue Liu, Xian-ping Li, Yuezhou Chen, Hui Ye, Xiaofeng Li, Zihan Lin, Zheng Wang, Wei Huang, Xia Ding*. Age-related changes changes in prevalence and symptom characteristics in kidney deficiency syndrome with varied health status:a cross-sectional observational study. Journal of traditional Chinese Medical Science, 2014,(1): 20-27. [Corresponding author]

  [14] Jianyu Wang, Xing Liu, Zhen Dou, Liang Chen, Hao Jiang, Chuanhai Fu, Guosheng Fu, Dan Liu, Jiancun Zhang, Tongge Zhu, Jingwen Fang, Jianye Zang, Jinke Cheng, Maikun Teng, Xia Ding* and Xuebiao Yao*. Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone HJURP. J Biol Chem. 2014, 289(12):8326-36. [Corresponding author]

  [15] Tongge Zhu, Zhen Dou, Bo Qin, Changjiang Jin, Xinghui Wang, Leilei Xu, Zhaoyang Wang, Lijuan Zhu, Fusheng Liu, Xinjiao Gao, Yuwen Ke, Zhiyong Wang, Felix Aikhionbare, Chuanhai Fu, Xia Ding* and Xuebiao Yao*. Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. J Biol Chem. 2013, 288(50):36149-59. [Corresponding author]

  [16] Zhao X, Wang D, Liu X, Liu L, Song Z, Zhu T, Adams G, Gao X, Tian R, Huang Y, Chen R, Wang F, Liu D, Yu X, Chen Y, Chen Z, Teng M, Ding X, Yao X*. Phosphorylation of the Bin, Amphiphysin, and RSV161/167 (BAR) domain of ACAP4 regulates membrane tubulation. Proc Natl Acad Sci U S A. 2013, 110(27):11023-8.

  科研项目获奖情况

  1) 2014年获得威尼斯手机版所有网站自然科学奖一等奖,第一完成人。

  2) 2014年荣获中国学位与研究生教育学会研究生教育成果奖二等奖,第四完成人。

  3) 2014年荣获科技部中青年科技创新领军人才称号

  4) 2015年荣获中国中西医结合学会科学技术奖三等奖,第一完成人。

  5) 2016年荣获2014-2015年度获农工民主党优秀党

  6) 2016年获世界中医药学会联合会消化病专业委员会优秀论文奖

  7) 2017威尼斯手机版所有网站第一届“杏林杯”创新创意创业大赛“优秀指导教师”

  8) 2017年获中华中医药学会科学技术奖二等奖(基于异病同治理论的多器官纤维化中医辨治体系研究)

  9) 2017年获“万人计划”科技创新领军人才称号

  10) 2018年获“岐黄杯第九届全国中医药博士生优秀论文评选活动”优秀论文指导老师

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